Human immunodeficiency virus (HIV) is a retrovirus that can lead to acquired immunodeficiency syndrome (AIDS, a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections). Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. The four major routes of transmission are unprotected sexual intercourse, contaminated needles, and transmission from an infected mother to her baby at birth, or through breast milk. If untreated, eventually most HIV-infected individuals develop AIDS and die; however about one in ten remains healthy for many years, with no noticeable symptoms.Treatment with anti-retrovirals, where available, increases the life expectancy of people infected with HIV.

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